Melanocortin-4 Receptor Gene Variant I103 Is Negatively Associated with Obesity
نویسندگان
چکیده
منابع مشابه
Melanocortin-4 receptor gene variant I103 is negatively associated with obesity.
Several rare mutations in the melanocortin-4 receptor gene (MC4R) predispose to obesity. For the most common missense variant V103I (rs2229616), however, the previously reported similar carrier frequencies in obese and nonobese individuals are in line with in vitro studies, which have not shown a functional implication of this variant. In the present study, we initially performed a transmission...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2004
ISSN: 0002-9297
DOI: 10.1086/382490